Human Pan-Cancer Focus Gene Mutation Test Kit
Genecast Focus is a multiplex PCR-based targeted sequencing assay designed to simplify the evaluation of somatic variants across 41 driver genes and microsatellite instability (MSI) in tissue samples from patients with non-small cell lung cancer, colorectal cancer and other solid tumors.
SNV, Indel, CNV and MSI are detected from FFPE DNA, while fusion and rearrangement are detected from FFPE RNA. The kit accurately and rapidly provides patients with mutation information relevant to targeted drugs, immunotherapy drugs and Lynch syndrome screening. The panel is also compatible with degraded samples, including DNA and RNA isolated from FFPE tissues.
Key Features and Benefits
Comprehensive Coverage
Targets over 900 hotspots across 41 genes and MSI focusing on known pan-cancer druggable targets.
Superb Performance
Detects RNA fusion/rearrangement as low as 100 copies using just 50 ng of RNADetects somatic mutations as low as 1% variant allelefrequency using just 10 ng of DNA
Fast, Streamlined Workflow
Generates sequencing-ready libraries in just 5 hours using a rapid,five-step protocol
Gene List
Specifications